RWD142 Prospective Monitoring of Patients with COVID-19 Vaccination for Outcomes of Hospitalization Using Electronic Medical Record Network

To assess if patients that received two doses of COVID-19 vaccination were at higher risk for hospitalization compared to who an additional booster vaccine using real-world data from electronic medical record network. We utilized the TriNetX federated network de-identified health identify receiving October 2022-November 2022. identified 1,995,566 fully vaccinated and 1,639,750 a combination CVX term or CPT, ICD-10-PCS, SNOMED procedural occurring. Fully shot-receiving analyzed 1:1 propensity score-matched adjust potential confounders. Hazard ratios (HR) evaluated significance 95% confidence intervals (CI). identified. After one month prospective monitoring, 17,282 22,107 shot incident patients, respectively identified, enrolled in cohort analysis. The adjusted HR with CI was 1.091 (1.08, 1.101). This pairwise comparison suggests increased vaccination. Using source, there statistically significant found among patients.